Longevity

Taurine

Conditionally essential amino acid with emerging longevity evidence. The 2023 Science paper showed taurine decline correlates with aging across species.

Studies Referenced16+
Total Participants700+
Outcomes Evaluated4
Known Interactions3

Evidence by Outcome

Longevity (animal)

Moderate Evidence

10-12% lifespan increase in mice (Science 2023)

1 studies

Exercise Performance

Moderate Evidence

Improved time to exhaustion at 1-6g/day

10 studies500 participants

Cardiovascular

Emerging Evidence

Blood pressure reduction, improved endothelial function

5 studies200 participants

Longevity (human)

Insufficient Evidence

No human longevity trials yet

Dosing Guide

Standard Dose

1-3g/day

Timing

Any time, often pre-workout

Can take on empty stomach

The Science 2023 paper used ~1000mg/kg/day in mice. Human-equivalent unclear. 1-3g/day is reasonable extrapolation.

Safety Profile

Overall Safety:Excellent

Possible Side Effects

  • Generally none at recommended doses

Contraindications

  • None established
Upper Limit: 6g/day used safely in studies

Known Interactions

Both target aging pathways — NMN via NAD+ restoration, taurine via mitochondrial function. No negative interactions known.

Source: Singh et al., Science 2023; Yoshino et al., Science 2021

🟢synergy+ Magnesium

Taurine enhances magnesium transport into cells. Magnesium taurate combines both in one molecule.

Source: Biol Trace Elem Res, 2018

🟢synergy+ Caffeine

Classic energy drink combination. Taurine may attenuate caffeine's cardiovascular effects while preserving cognitive benefits.

Source: Amino Acids, 2014

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