Supplement Database
Evidence profiles for 12 supplements. Each entry includes clinical evidence grades, dosing guidance, safety data, and known interactions.
Creatine Monohydrate
The most researched sports supplement in history. Increases phosphocreatine stores for ATP regeneration during high-intensity exercise.
Vitamin D3
A prohormone essential for calcium metabolism, immune function, and gene expression. Deficiency affects ~1 billion people worldwide.
Omega-3 (EPA/DHA)
Essential polyunsaturated fatty acids with roles in inflammation, cardiovascular function, and brain structure.
Magnesium
Essential mineral involved in 300+ enzymatic reactions. ~50% of adults are deficient. Form matters significantly for absorption and target effect.
Ashwagandha (KSM-66)
Adaptogenic herb (Withania somnifera) with clinical evidence for cortisol reduction, stress management, and anxiolytic effects.
NMN (Nicotinamide Mononucleotide)
NAD+ precursor that restores cellular NAD+ levels, which decline with age. Central to longevity research but human data is still early.
CoQ10 / Ubiquinol
Essential cofactor in mitochondrial electron transport chain. Levels decline with age and statin use. Ubiquinol is the reduced (active) form.
Caffeine
Adenosine receptor antagonist. The most consumed psychoactive substance worldwide. Well-established ergogenic aid.
L-Theanine
Amino acid found in tea leaves. Promotes alpha brain wave activity for relaxed alertness without sedation. Synergistic with caffeine.
Vitamin K2 (MK-7)
Activates osteocalcin (calcium to bones) and matrix GLA protein (prevents arterial calcification). Essential D3 companion.
Taurine
Conditionally essential amino acid with emerging longevity evidence. The 2023 Science paper showed taurine decline correlates with aging across species.
Whey Protein
Complete protein with high leucine content. Gold standard for muscle protein synthesis stimulation. Isolate vs concentrate affects purity and lactose content.